Baker KT, Nachmanson D, Kumar S, Emond MJ, Ussakli C, Brentnall TA, Kennedy SR, Risques, RA. Mitochondria DNA mutations are associated with ulcerative colitis preneoplasia but tend to be negatively selected in cancer. Mol Cancer Res. 2019 Feb;17(2):488- 498. doi: 10.1158/1541-7786.MCR-18-0520. PMID: 30446624
Baker KT, Salk JJ, Brentnall TA, Risques RA. Precancer in Ulcerative Colitis: The Role of the Field Effect and its Clinical Implications. Carcinogenesis. 2018 Jan 12;39(1):11-20. doi: 10.1093/carcin/bgx117. PMID: 29087436
Nachmanson D, Lian S, Schmidt EK, Hipp MJ, Baker KT, Zhang Y, Tretiakova M, Loubet-Senear K, Kohrn BF, Salk JJ, Kennedy SR, Risques RA. Targeted genome fragmentation with CRISPR/Cas9 enables fast and efficient enrichment of small genomic regions and ultra-accurate sequencing with low DNA input (CRISPR-DS). Genome Res. 2018 Oct;28(10):1589-1599. doi: 10.1101/gr.235291.118. Epub 2018 Sep 19. PMID: 30232196
Nachmanson D, Lian S, Schmidt EK, Hipp MJ, Baker KT, Zhang Y, Tretiakova M, Loubet-Senear K, Kohrn BF, Salk JJ, Kennedy SR, Risques RA. CRISPR-DS: An efficient, low DNA input method for ultra-accurate sequencing. bioRxiv 207027; doi: 10.1101/207027.
Salk JJ, Loubet-Senear K, Maritschnegg E, Valentine CC, Williams LN, Higgins JE, Horvat R, Vanderstichele A, Nachmanson D, Baker KT, Emond MJ, Loter E, Tretiakova M, Soussi T, Loeb LA, Zeilinger R, Speiser P, Risques RA. Ultra-sensitive TP53 sequencing for cancer detection reveals progressive clonal selection in normal tissue over a century of human lifespan. Cell Rep. 2019 Jul 2;28(1):132-144.e3. doi: 10.1016/j.celrep.2019.05.109. PMID: 31269435